CLEFT LIP AND PALATE


Who first discovered cleft lip and palate?
Dr. Nagato Natsume discovered cleft lip and palate.


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Under what circumstances was cleft lip and palate discovered?
Cleft lip and palate was discovered when Greeks, Romans and Spartans came across the disorder. They believed that it was based on religion and superstition. The Romans and Spartans would kill the children if it was born with the disorder while the Greeks were the first ones to introduce a medical procedure.
What are the symptoms/characteristics associated with cleft lip and palate?
When you have cleft lip and palate you have difficulty talking. This can be fixed when the patient goes to speech therapy. Also, you have trouble swallowing food and liquid. Since people with cleft lip and palate have a hard time eating it causes some of their food to come out of their nose.


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At what age do the cleft lip and palate symptoms begin?
When the women is pregnant the two side of the lip fuse together around the fifth to sixth week. When the child is born the symptoms are present.
Are cleft lip and palate symptoms treatable?
Yes, cleft lip and palate symptoms are treatable with surgery. When you get this type of surgery it leaves a small scar on the upper lip and nose. Children with this disorder get this surgery anywhere from when they are 9 months old to when they are 6 years old.
Is cleft lip and palate a fatal disorder?
No, cleft lip and palate is not a fatal disorder because you do not die from it.
What is the inheritance pattern of cleft lip and palate disorder?
Twice as many males get cleft lip and palate than females do.
Are there any environmental factors that can affect the symptoms for cleft lip and palate (either aggravate or alleviate)?
Yes, when the women is pregnant and she smokes she is at a higher risk of delivering a baby with cleft lip and palate. Also , if the women has diabetes or takes medication the baby has a possibility of having cleft lip and palate.
How common is cleft lip and palate disorder?
One in seven hundred babies are born with cleft lip and palate disorder.
Does cleft lip and palate occur more frequently in certain parts of the world or in certain ethnic groups or in one sex?
Cleft lip and palate mainly occurs in males. In a study it shows that it is the most common in Native Americans and least common in African-Americans.
What tests are done to confirm a diagnosis of this disorder?
The test that are used to determine if your child have cleft lip and palate are lab tests on urine, blood, and other bodily fluids also, there can be an x-ray, biopsy, MRI, CAT scans, and ultrasounds.
Which chromosome(s) is responsible for cleft lip and palate disorder?
The sex chromosomes is responsible for cleft lip and palate.

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Is cleft lip and palate caused by a gene mutation?
Yes, cleft lip and palate is caused by a gene mutation.
Which gene is involved in cleft lip and palate?
The allele is involved in cleft lip and palate.
Is cleft lip and palate disorder caused by a chromosomal mutation? Which type: nondisjunction, deletion, inversion, etc.?
Cleft lip and palate is caused by a spontaneous mutation.

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https://www.mayoclinic.org/diseases-conditions/cleft-palate/symptoms-causes/syc-20370985


https://www.cdc.gov/ncbddd/birthdefects/cleftlip.html


https://kidshealth.org/en/teens/cleft.html


http://hihg.med.miami.edu/code/http/modules/education/Design/SubSlide.asp?ID=147


https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2825059/